منابع مشابه
Angiotensin II-dependent superoxide: effects on hypertension and vascular dysfunction.
Dysfunction Dependent Superoxide : Effects on Hypertension and Vascular − Angiotensin II Print ISSN: 0194-911X. Online ISSN: 1524-4563 Copyright © 2008 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Hypertension doi: 10.1161/HYPERTENSIONAHA.107.090472 2008;52:51-56; originally published online May 12...
متن کاملAngiotensin II mediates LDL-induced superoxide generation in mesangial cells.
Lipid abnormalities and activation of the local renin-angiotensin system (RAS) may be involved in the pathogenesis of chronic glomerular disease. This study investigated whether low-density lipoprotein (LDL) activates local RAS in cultured human mesangial cells (HMC) and, at the same time, whether ANG II mediates LDL-induced mesangial cell proliferation, hypertrophy, and superoxide (O2-) genera...
متن کاملExtracellular superoxide dismutase depletion in hypertension unmasks a new role for angiotensin II in regulating Cu,Zn-superoxide dismutase activity.
While studying the effects of 2 weeks of angiotensin II infusion in extracellular superoxide dismutase knockout (ecSOD / ) mice on increasing superoxide and promoting hypertension, Gongora et al1 made the surprising observation that NO production and its associated endothelium-dependent relaxation were actually improved by angiotensin II treatment in aorta from these mice without altering the e...
متن کاملInvestigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries.
BACKGROUND Increased vascular superoxide anion (.O(2)(-)) production contributes to endothelial dysfunction and hypertension in animal models of cardiovascular disease. Observations in experimental animals suggest that angiotensin II (Ang II) increases.O(2)(-) production by activation of vascular NAD(P)H oxidase. We studied the sources of.O(2)(-) production in human blood vessels and investigat...
متن کاملIncreases Superoxide Production in Human Internal Mammary Arteries Investigation Into the Sources of Superoxide in Human Blood Vessels : Angiotensin II
Colin Berry, Carlene A. Hamilton, M. Julia Brosnan, Fergus G. Magill, Geoffrey A. Berg, John Increases Superoxide Production in Human Internal Mammary Arteries Investigation Into the Sources of Superoxide in Human Blood Vessels : Angiotensin II Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2000 American Heart Association, Inc. All rights reserved. is published by the American Heart ...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2008
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.107.090472